Basic Information
VIS ID
TVIS44018463
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
82068450/82813442 (Hg38)
End
82068450/82813442 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/3912193; hsa-mir-105-1/Downstream/1412310;
Nearest TSS
ENST00000429181/Upstream/1557948; ENST00000373200/Downstream/694819;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1809448, chrX-CpG: 63/Downstream/695121
Nearby gene
POU3F4(+694819) ;
Upstream sequence
aaaccaccacagcacgtgtatacctatgtaataaacctgcatgttctgcacatgtatcccagaacttcaaatataattaaaaaaaTTAGGAATGCCATTC
Downstream sequence
TTACTCTGCCAAGCATAAAAGGATAAATACCTACATATTTCATGTATCTATATACCTGGACTCAAGAAAACTCTTATGCCAATTCCATTGATTCAGTGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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