Basic Information
VIS ID
TVIS44018466
Fusion event
HTLV-1-TEX16P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
84007246/84752238 (Hg38)
End
84007246/84752238 (Hg38)
Orient
+
Location type
Intronic
Target gene
TEX16P
Nearest miRNA
hsa-let-7f-2/Upstream/526410; hsa-mir-105-1/Downstream/1083542;
Nearest TSS
ENST00000429181/Upstream/249759; ENST00000373173/Downstream/251588;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/563722, chrX-CpG: 46/Downstream/181821
Nearby gene
UBE2DNL(+181911) ;
Upstream sequence
TCTGGGCTGGCAAAAGAGATATCAAACaatttgaccaattgacatttgtagaacactttactcaaggacagcagaatacatattcctgtctagtacacat
Downstream sequence
agaaaatttaccaagataccccatattctaggccataagacatttctcaataaatttaagaggattcaagtcatataaagtatgttctctgaccagactg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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