Basic Information
VIS ID
TVIS44018478
Fusion event
HTLV-1-USP9Y integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
14851903/12739969 (Hg38)
End
14851903/12739969 (Hg38)
Orient
+
Location type
Intronic
Target gene
USP9Y
Nearest miRNA
hsa-mir-3690-2/Upstream/8133741; hsa-mir-12120/Downstream/739208;
Nearest TSS
ENST00000430575/Upstream/30533; ENST00000453031/Downstream/107076;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/202235, chrY-CpG: 52/Downstream/164664
Upstream sequence
ATTTCTTTGAATTCATTTCCACTGGTAATTTTCATTTTGACTTTGGTTAAAATAACCTGTAGAAATGCAGAGAATAATTGGAAAATGAGGCATAAAACAT
Downstream sequence
TCTGGTTCTATGGAGTTATGTATATGGCATATAGAAATGAAATTCAAAAAACAAGAGGTTTCTAATATCATAATGTCACTTTTAAAGACATTTTGGCACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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