Basic Information
VIS ID
TVIS44018479
Fusion event
HTLV-1-UTY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
15422827/13310947 (Hg38)
End
15422827/13310947 (Hg38)
Orient
+
Location type
Intronic
Target gene
UTY
Nearest miRNA
hsa-mir-3690-2/Upstream/8704719; hsa-mir-12120/Downstream/168230;
Nearest TSS
ENST00000430575/Upstream/395451; ENST00000284856/Downstream/168557;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/405560, chrY-CpG: 33/Downstream/168432
Upstream sequence
ggaagccaaggtgggcagatcatgaggtcaggagatccagaccaccctggctaacacggtgaaatcccgtctctactaaaaatacaaaaatattaggtgg
Downstream sequence
atgtggtggcacaggcggtaatcccagctactcgggaggctgaggcaggtgaatggcatgaacccaggaggcagagcttgcagtgagccgagatcgcacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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