Basic Information
VIS ID
TVIS44018484
Fusion event
HTLV-1-RBMY2KP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
8132566/8264525 (Hg38)
End
8132566/8264525 (Hg38)
Orient
+
Location type
Intronic
Target gene
RBMY2KP
Nearest miRNA
hsa-mir-3690-2/Upstream/3658297; hsa-mir-12120/Downstream/5214652;
Nearest TSS
ENST00000430575/Upstream/459601; ENST00000413486/Downstream/373769;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/704142, chrY-CpG: 23/Downstream/15311
Nearby gene
TTTY18(-418845) ;
Upstream sequence
ACCTATTATTTTGAATATTTGCTTTAATACCTGCTTCGGTCTCCTTTTTCAGATCGACTTTCCCCATCATCTCCTGTAGATGCCACATATCTTGAGCTAC
Downstream sequence
CATATGCTTCACGAGGAGCAGGGTGCACCCTATCCAGAGAAGGTGGATTCCTTTGGTCTTTTCTGCCAATGTGCTCACGACCACAGGAATAAAAATCACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate