Basic Information
VIS ID
TVIS44018495
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
107110159/106567537 (Hg38)
End
107110159/106567537 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/6286229; hsa-mir-11399/Downstream/1329686;
Nearest TSS
ENST00000473358/Upstream/486376; ENST00000415910/Downstream/250702;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/486305, chr1-CpG: 104/Downstream/489046
Nearby gene
PRMT6(+489108) ;
Upstream sequence
TCAATTAACTCTGTCCGTAGATACTTTTCATACAAGTAGTGAAATAAATCATAATAACTACTTATCACCGATTATTACTTAAAGCATTTTTTTTTGTTTC
Downstream sequence
TGTGTACTACTTCTTGTTCATTTCCTAGATAAATTTCAATGGCTAAGACTTTTATGTCAGGGTCACTTTCTATTAGATAATGCTGACACAAAAATGTTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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