Basic Information
VIS ID
TVIS44018497
Fusion event
HTLV-1-NTNG1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
107722324/107179702 (Hg38)
End
107722324/107179702 (Hg38)
Orient
-
Location type
Intronic
Target gene
NTNG1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-129-5p ; hsa-mir-2054 ; hsa-mir-3613-5p ; hsa-mir-6885-3p
Nearest miRNA
hsa-mir-101-1/Upstream/6898394; hsa-mir-11399/Downstream/717521;
Nearest TSS
ENST00000473358/Upstream/31108; ENST00000477948/Downstream/81101;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/37861, chr1-CpG: 22/Downstream/300908
Upstream sequence
tatttgaagttcaagggtacaagtgcaggtttgttacacaggtaaacttgtgtcataggggtttgttgtctagattatttcatcacccaagtattaaaac
Downstream sequence
tagcactattagttatttttcctgatcctctccctcctcctcaccctccaccctccGAAATATTAATGGAATTACTTTAATATTCTTTTCTGCTTCCTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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