Basic Information
VIS ID
TVIS44018519
Fusion event
HTLV-1-CD58 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
117112411/116569789 (Hg38)
End
117112411/116569789 (Hg38)
Orient
+
Location type
Intronic
Target gene
CD58
Nearest miRNA
hsa-mir-101-1/Upstream/9678; hsa-mir-1182/Downstream/101957;
Nearest TSS
ENST00000473358/Upstream/25199; ENST00000624685/Downstream/1195;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/35112, chr1-CpG: 98/Downstream/549
Upstream sequence
ctccgggactcaggtgattctcccacctcagccttccgagtagctgggactataggtatgcgccaccacgctcagctaatttttgtattttttgtagagc
Downstream sequence
cgatctttcaccgtgttggccctgctggtctccgattcctggcctcaagtgatccacctgcctcagcctcccaaagtgctaggatgacaggtgtaagcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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