Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene117738223117953861118185223117863485117929630117929720117966542117928385117931250117925801117926600117961723
Basic Information
VIS ID
TVIS44018520
Fusion event
HTLV-1-SPAG17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
118504346/117961723 (Hg38)
End
118504346/117961723 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPAG17
Nearest miRNA
hsa-mir-101-1/Upstream/866995; hsa-mir-1182/Downstream/27888864;
Nearest TSS
ENST00000473358/Upstream/31948; ENST00000423984/Downstream/3087;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/31626, chr1-CpG: 23/Downstream/223470
Upstream sequence
TTTTCTTCTAGGCTCAGATATGCAGTCCTTGTGGCTTGCCGATTTGTGTCCCAAACCACAAGTCTTAATGTTCTTGAGCATAACACAATCACTGAAGTGA
Downstream sequence
GTAAGGGATGCAGTGGTGTTATTTGTTGGGCAGAATAAATAAGTGAATTTTGGCATAGAGTTTCTGAAGGCATAACTATGAAGGCAAGAGAATAGGCAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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