Basic Information
VIS ID
TVIS44018527
Fusion event
HTLV-1-HMGCS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
120308376/119765753 (Hg38)
End
120308376/119765753 (Hg38)
Orient
+
Location type
Intronic
Target gene
HMGCS2
Nearest miRNA
hsa-mir-101-1/Upstream/2671025; hsa-mir-1182/Downstream/26084834;
Nearest TSS
ENST00000473358/Upstream/1127; ENST00000608123/Downstream/3141;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/53104, chr1-CpG: 21/Downstream/87433
Upstream sequence
attattgtcatatactttacttctacatgttataagcccttatagggcataattatacaatctttactcattttaaaagtgtacctctaattacatgtct
Downstream sequence
ttctcctttcttttTTCTACACAAGAACATACCCACTGTTTTCCTACTTTTAAGTAAGTTTTCTGCTAGCTGATTTTTCTGATAGGGCCTTCCaatgttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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