Basic Information
VIS ID
TVIS44018544
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
153506128/153533652 (Hg38)
End
153506128/153533652 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1F
Nearest miRNA
hsa-mir-101-1/Upstream/1987761; hsa-mir-1182/Downstream/156053;
Nearest TSS
ENST00000473358/Upstream/49; ENST00000436839/Downstream/2339;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/271815, chr1-CpG: 40/Downstream/2296
Nearby gene
S100A6(-948) ;
Upstream sequence
ATAGAGAAGGAGGGCCTCCAAGAAGGTGCATCTCCCAGCTGTTTACCAATCCCCACCCAGTGGGGACAGAAGACAACTTAATTCCACAAAGTTGGACCCC
Downstream sequence
CAAGGGAAGTGGGGAGGTGAGAGGGAAAGAAGGATGTGGTCTCCATCTAAAGTCAAGATCTCTTCCCCAGAAGCTAGAGGTAAACTTGCCCAGCTCGGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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