VISDB Viral Integration Site DataBase

VIS ID

TVIS44018545

Fusion event

HTLV-1-TPM3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

154133914/154161438 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-145-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-218-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-2467-3p ; hsa-mir-4497 ; hsa-mir-6077 ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6768-5p ; hsa-mir-488-3p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-7110-5p ; hsa-mir-6752-5p ; hsa-mir-6842-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-6732-5p ; hsa-mir-9500 ; hsa-mir-4779 ; hsa-mir-3614-3p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-4648 ; hsa-mir-6801-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-7106-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-4294 ; hsa-mir-765 ; hsa-mir-6081 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6776-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6510-5p ; hsa-mir-6873-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-4515 ; hsa-mir-5195-3p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-570-3p ; hsa-mir-545-3p ; hsa-mir-371b-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-1276 ; hsa-mir-29b-2-5p ; hsa-mir-4717-3p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-4724-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4635 ; hsa-mir-4459 ; hsa-mir-4695-5p ; hsa-mir-665 ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-216b-5p ; hsa-mir-6715b-3p ; hsa-mir-6715a-3p ; hsa-mir-1273f ; hsa-mir-1302 ; hsa-mir-133a-3p ; hsa-mir-133b ; hsa-mir-181c-3p ; hsa-mir-197-5p ; hsa-mir-200c-5p ; hsa-mir-3132 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3196 ; hsa-mir-383-5p ; hsa-mir-4282 ; hsa-mir-4298 ; hsa-mir-4330 ; hsa-mir-4451 ; hsa-mir-4687-5p ; hsa-mir-4690-3p ; hsa-mir-506-5p ; hsa-mir-550a-3p ; hsa-mir-5685 ; hsa-mir-6758-3p ; hsa-mir-6816-5p ; hsa-mir-6832-5p ; hsa-mir-6835-5p ; hsa-mir-6843-3p ; hsa-mir-6848-3p ; hsa-mir-6861-5p ; hsa-mir-138-1-3p ; hsa-mir-146b-3p ; hsa-mir-3163 ; hsa-mir-3190-5p ; hsa-mir-339-5p ; hsa-mir-3926 ; hsa-mir-4421 ; hsa-mir-4684-5p ; hsa-mir-4786-3p ; hsa-mir-548s ; hsa-mir-5699-3p ; hsa-mir-593-3p ; hsa-mir-6779-3p ; hsa-mir-6818-3p ; hsa-mir-6895-3p ; hsa-mir-7843-3p

Nearest miRNA

hsa-mir-101-1/Upstream/56846; hsa-mir-1182/Downstream/32227;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/170404, chr1-CpG: 49/Downstream/21354

Upstream sequence

TACATATAGATCTCGTGAACAGCCTGAATTTAGATAATACCTATAACCAAGTTAGTTTGTGTGATTCTCACTTGGGAAAGAAGGATGTTATCAGGATCCt

Downstream sequence

ttttttttttttttttttttgagtttcactcttgttgcccaggttggagtgcaatggtacgattttggttcactgcaacctccacctcccaggttcaagc