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TVIS44018562
Basic Information
VIS ID
TVIS44018562
Fusion event
HTLV-1-POGK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
166810307/166841070 (Hg38)
End
166810307/166841070 (Hg38)
Orient
-
Location type
Exonic
Target gene
POGK
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-130b-3p
;
hsa-mir-218-5p
;
hsa-mir-93-5p
;
hsa-mir-18a-5p
;
hsa-mir-935
;
hsa-mir-296-3p
;
hsa-mir-99a-5p
;
hsa-mir-17-5p
;
hsa-mir-577
;
hsa-mir-4425
;
hsa-mir-450a-1-3p
;
hsa-mir-92a-1-5p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-3674
;
hsa-mir-5192
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-6770-5p
;
hsa-mir-4773
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-129-5p
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-6516-5p
;
hsa-mir-29b-2-5p
;
hsa-mir-6811-5p
;
hsa-mir-6511b-5p
;
hsa-mir-6077
;
hsa-mir-7-5p
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-490-5p
;
hsa-mir-8068
;
hsa-mir-5692a
;
hsa-mir-1295b-5p
;
hsa-mir-1912
;
hsa-mir-4645-5p
;
hsa-mir-4650-5p
;
hsa-mir-4673
;
hsa-mir-5701
Nearest miRNA
hsa-mir-101-1/Upstream/686272; hsa-mir-1182/Downstream/1157590;
Nearest TSS
ENST00000473358/Upstream/981;
ENST00000487826/Downstream/22146;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/963
,
chr1-CpG: 84/Downstream/34689
Upstream sequence
CTACCCTCTCAATTTGAGCCTGAAAGAAGAGGAAGAGGAAGAAGAGATTCAGAGCCGGGAACTAGAGGACGGCCCGGCAGACATGCAGAAAGTACGAATC
Downstream sequence
TGCTCTGAGGGCGGATGGGTAAGTAAGAAGGTGTGGAGTCCACACAGCCAGCAGATGCAGGCCTGAGAGCCCAGCTTGCTTTAAGTCTCCTCCTCAGACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#2
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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