VISDB Viral Integration Site DataBase

VIS ID

TVIS44018574

Fusion event

HTLV-1-ABL2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

179196382/179227247 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-140-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-92a-3p ; hsa-mir-20a-5p ; hsa-mir-4755-5p ; hsa-mir-5006-3p ; hsa-mir-6829-3p ; hsa-mir-6874-5p ; hsa-mir-6791-3p ; hsa-mir-3121-5p ; hsa-mir-4761-5p ; hsa-mir-3908 ; hsa-mir-6507-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-139-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-548e-5p ; hsa-mir-107 ; hsa-mir-6081 ; hsa-mir-2861 ; hsa-mir-939-3p ; hsa-mir-7851-3p ; hsa-mir-649 ; hsa-mir-490-3p ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-6773-3p ; hsa-mir-5693 ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-500b-3p ; hsa-mir-4279 ; hsa-mir-2355-5p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-122-3p ; hsa-mir-4446-5p ; hsa-mir-642a-5p ; hsa-mir-6826-3p ; hsa-mir-570-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-660-3p ; hsa-mir-526b-5p ; hsa-mir-6868-3p ; hsa-mir-6861-3p ; hsa-mir-4751 ; hsa-mir-6870-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-125a-5p ; hsa-mir-26a-1-3p ; hsa-mir-188-3p ; hsa-mir-605-5p ; hsa-mir-7849-3p ; hsa-mir-8485 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-3672 ; hsa-mir-4294 ; hsa-mir-6864-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-101-1/Upstream/549413; hsa-mir-1182/Downstream/576677;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/144434, chr1-CpG: 73/Downstream/1781

Nearest cancer related gene

ABL2(OG, No orient, 0)

Upstream sequence

ATTTTCTTTCTACTGCTTCTTAATtagaatcataaaatcttaaaaccagaaagtatcttagagatcatccagtccaacctcctcactttacagataaaga

Downstream sequence

aacccaaagatggtgactaaaatcacccaggcaggtggAGCCAGAACCAGAACTTGACTCTTCCAATTTTTGCTCTATGATCTTTTTCTTCCAACTCATA