Basic Information
VIS ID
TVIS44018588
Fusion event
HTLV-1-BRINP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
190385213/190416083 (Hg38)
End
190385213/190416083 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
BRINP3
Nearest miRNA
hsa-mir-101-1/Upstream/9977693; hsa-mir-1182/Downstream/2300245;
Nearest TSS
ENST00000473358/Upstream/151185; ENST00000436905/Downstream/58718;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/3735134, chr1-CpG: 56/Downstream/2392419
Upstream sequence
TTTACAGGTTTTCTTCTACTGTGTCTCAGCCACATTCAATATGTTCCTAAGTTAAAATACATTTTGGTCCCCCTTGAATGCCTTTTAAGTTGACATATGG
Downstream sequence
CACACCACATGAAATCTTAATTAAGTGATGATTACCTTAATACACAAATCCATTAGGTTGTCTCAATAACTATAAACACCTTCAAAGGTTCATGTCATTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate