Basic Information
VIS ID
TVIS44018592
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
200363369/200394241 (Hg38)
End
200363369/200394241 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1535088; hsa-mir-1182/Downstream/1325267;
Nearest TSS
ENST00000473358/Upstream/19887; ENST00000635220/Downstream/6464;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/91831, chr1-CpG: 42/Downstream/15530
Nearby gene
ZNF281(-10706) ;
Upstream sequence
TGCAAATAGATTTGTCCTCATGAAGGAAATTAGGCGGATCTCAAACCCTAAATACCACATAGTAATCCTAAATCTGTCGTCATAATTAAGCCAGAAATTA
Downstream sequence
TCCAGTATATACCAGGTTTATTAGAGATTTGAGTAAAACCTACTGATGCTTCTAACACTCCATTAGTGAAtttttttttttttttgagacggagtctctc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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