VISDB Viral Integration Site DataBase

VIS ID

TVIS44018598

Fusion event

HTLV-1-MAPKAPK2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

206894533/206721188 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-324-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-3680-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-483-3p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-8064 ; hsa-mir-1207-5p ; hsa-mir-1233-5p ; hsa-mir-1253 ; hsa-mir-1909-3p ; hsa-mir-3196 ; hsa-mir-4300 ; hsa-mir-4468 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4651 ; hsa-mir-4763-3p ; hsa-mir-483-5p ; hsa-mir-5001-5p ; hsa-mir-5591-5p ; hsa-mir-6081 ; hsa-mir-608 ; hsa-mir-6090 ; hsa-mir-6722-3p ; hsa-mir-6726-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6778-5p ; hsa-mir-6782-5p ; hsa-mir-6820-5p ; hsa-mir-6827-5p ; hsa-mir-762 ; hsa-mir-920 ; hsa-mir-3128 ; hsa-mir-4720-5p ; hsa-mir-4799-3p ; hsa-mir-5588-5p ; hsa-mir-6757-3p ; hsa-mir-6868-5p

Nearest miRNA

hsa-mir-101-1/Upstream/246324; hsa-mir-1182/Downstream/1080664;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/34882, chr1-CpG: 63/Downstream/188160

Upstream sequence

gccatgggggtaggtccctcgtgaatggcttggtgctgttcttaagatagtgagttcttaggagatctggttgtttaaaagtgggtggcaccccacccct

Downstream sequence

gttgctcctgctcttgccatgtgacatccctgctcccccttcaccttccaccatgattgtaagcttcctgaggcctcaccaaaagcagatactagtgcca