Basic Information
VIS ID
TVIS44018603
Fusion event
HTLV-1-HSD11B1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
209850344/209676999 (Hg38)
End
209850344/209676999 (Hg38)
Orient
+
Location type
Intronic
Target gene
HSD11B1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/53489; hsa-mir-1182/Downstream/2400614;
Nearest TSS
ENST00000473358/Upstream/1579; ENST00000615289/Downstream/9179;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/916, chr1-CpG: 28/Downstream/70609
Nearby gene
G0S2(+609) ;
Upstream sequence
CACCAAAGCAGATGATGAGTCTAGCTCTACCCAGCCTTCCTCCCCACGAATCCAGATCATAGTAAGAAACTCTGGGCTAGAAAGAGAAAAAAACCGGTTG
Downstream sequence
TTACATATCTGAGTCCTCCTCCTCCAGTGTACAGAGCTTCATCTGTAGTAATAGCTAATTCAGTGACTCTATAGGGCTCAGCAAAACAAATTTTAAACTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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