Basic Information
VIS ID
TVIS44018606
Fusion event
HTLV-1-LOC105372912 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
213972803/213799460 (Hg38)
End
213972803/213799460 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372912
Nearest miRNA
hsa-mir-101-1/Upstream/1721775; hsa-mir-1182/Downstream/6318393;
Nearest TSS
ENST00000473358/Upstream/68044; ENST00000607726/Downstream/127194;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/409845, chr1-CpG: 42/Downstream/180411
Nearby gene
PROX1-AS1(No orient, 20181)
Upstream sequence
TTGTGGCCTTTTTGTAAGCAGCAGCTACTGTTGACTTGAGCCATTGGGCCTAGAGATCATCCCGACCTGAGCTTCCCATTAGCAAGCTGGGAATGGGCTG
Downstream sequence
GACGCTGGCTAACAGGTCTTATTACTAAACTATATTTGATGAATGTGATGATAGTTAAAATTTTCTACTTAAAAAAAGAAAACTATAGGAAATTTCCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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