Basic Information
VIS ID
TVIS44018624
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
225866520/225678818 (Hg38)
End
225866520/225678818 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/1280507; hsa-mir-1182/Downstream/243262;
Nearest TSS
ENST00000473358/Upstream/25676; ENST00000448264/Downstream/21786;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1192, chr1-CpG: 35/Downstream/98810
Nearby gene
ENAH(-25675) ;
Upstream sequence
AAAATATTCATGTTGAATGTGTTAATGTACTGAAATTGTCAACATTTTTACTTACAGACTGTCTTACAGCGTAATTTGCCCAAGGCCTGATGTTATGAAC
Downstream sequence
TGCCTCCTTTTTTTTTTTTTAATTCATGAAGAACTTGTAACATAATCCCATTTCAGTCAAATTGAAAACTCAGGTTTAAAACATTGCTGTTCAGAGGTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate