Basic Information
VIS ID
TVIS44018634
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
23858326/23531834 (Hg38)
End
23858326/23531834 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/487462; hsa-mir-101-1/Downstream/397236;
Nearest TSS
ENST00000473358/Upstream/614; ENST00000612756/Downstream/19081;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/237, chr1-CpG: 76/Downstream/22692
Nearby gene
E2F2(-614) ;
Nearest cancer related gene
E2F2(TSG, -614) ;
Upstream sequence
CTTTAATGGCAGAGGGGTGAGGGACGGAGGCAAACTAGTCTACTTCTTTGTAGGGaaaactaacatctattcagcgcctacaggatgccaggcaccatgc
Downstream sequence
tagatccttacaagcgttgttttagttaatttattccaacaatcctgggaagaggaatgatgatccccatgataaagactgacagtctgaaaggctgggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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