Basic Information
VIS ID
TVIS44018647
Fusion event
HTLV-1-WASF2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
End
27734791/27408297 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-1224-5p ; hsa-mir-940 ; hsa-mir-877-3p ; hsa-mir-425-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4713-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-627-3p ; hsa-mir-5003-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-629-3p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-4279 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-1343-5p ; hsa-mir-143-5p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-1914-3p ; hsa-mir-197-3p ; hsa-mir-214-3p ; hsa-mir-3173-3p ; hsa-mir-3184-5p ; hsa-mir-3610 ; hsa-mir-3612 ; hsa-mir-3619-5p ; hsa-mir-3944-5p ; hsa-mir-412-3p ; hsa-mir-423-5p ; hsa-mir-4261 ; hsa-mir-4300 ; hsa-mir-4424 ; hsa-mir-4487 ; hsa-mir-4514 ; hsa-mir-4690-5p ; hsa-mir-4692 ; hsa-mir-4695-5p ; hsa-mir-5188 ; hsa-mir-5194 ; hsa-mir-541-3p ; hsa-mir-5582-5p ; hsa-mir-5591-5p ; hsa-mir-6072 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-654-5p ; hsa-mir-6721-5p ; hsa-mir-6726-5p ; hsa-mir-6728-3p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6754-3p ; hsa-mir-6891-3p ; hsa-mir-6891-5p ; hsa-mir-761 ; hsa-mir-875-3p ; hsa-mir-920 ; hsa-mir-939-5p ; hsa-mir-96-3p ; hsa-mir-1276 ; hsa-mir-1910-5p ; hsa-mir-216b-3p ; hsa-mir-24-3p ; hsa-mir-3120-3p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3614-5p ; hsa-mir-3677-5p ; hsa-mir-4264 ; hsa-mir-4286 ; hsa-mir-4304 ; hsa-mir-4311 ; hsa-mir-4438 ; hsa-mir-451b ; hsa-mir-455-3p ; hsa-mir-4696 ; hsa-mir-484 ; hsa-mir-5095 ; hsa-mir-583 ; hsa-mir-626 ; hsa-mir-6873-5p ; hsa-mir-6876-3p ; hsa-mir-7151-3p ; hsa-mir-8064 ; hsa-mir-9500 ; hsa-mir-1304-3p ; hsa-mir-1307-3p ; hsa-mir-3615 ; hsa-mir-4284 ; hsa-mir-4512 ; hsa-mir-4638-5p ; hsa-mir-4757-5p ; hsa-mir-505-5p ; hsa-mir-6741-3p ; hsa-mir-6744-3p
Nearest miRNA
hsa-mir-12136/Upstream/853704; hsa-mir-101-1/Downstream/3330859;
Upstream sequence
CCAGTCGTCCTCATCAAATTCAGAGGAGTCATCTTCTGAGTCACTGTACTCAACAGCAATGCGACGAGACAAGATGGTGGCCACGTCATTGCCCACAACA
Downstream sequence
TCCCGCTTCTCTTGTTCCCGCTGCTCCTCAACCCTGCGCAGCTGAAAACCTAGTGGCAAAGAGACAGAAGGGTGAGGAAGGCGTGTCCTCAGCCTTGGAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate