Basic Information
VIS ID
TVIS44018680
Fusion event
HTLV-1-LOC101926944 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.1
Reference genome
GRCh37/hg19
Start
60248911/59783239 (Hg38)
End
60248911/59783239 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA1B
Target gene
LOC101926944
Nearest miRNA
hsa-mir-12136/Upstream/49943; hsa-mir-101-1/Downstream/2062836;
Nearest TSS
ENST00000473358/Upstream/27567; ENST00000455990/Downstream/5943;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/486117, chr1-CpG: 90/Downstream/31176
Upstream sequence
GAGGACATTTACTGAAGTGTTCTGTATATCTTTGTATTTCTCACAATATCAGGAATGGGTTGTCCACAGATATTTTTGAATCTATAATAAATGGTGAACA
Downstream sequence
CCAATGAGCATGGCACCATTGGGTCTGCCAGTCCTCCTGGAGCATGTCTGGTTCTGAATGTCAGAACATTAATATTTTCATTGGGAAAATGTGAGTCTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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