Basic Information
VIS ID
TVIS44018684
Fusion event
HTLV-1-LINC00466 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
63631162/63165491 (Hg38)
End
63631162/63165491 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA1L
Target gene
LINC00466
Nearest miRNA
hsa-mir-12132/Upstream/1086632; hsa-mir-101-1/Downstream/161434;
Nearest TSS
ENST00000473358/Upstream/26241; ENST00000449140/Downstream/84429;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/476813, chr1-CpG: 599/Downstream/151232
Upstream sequence
GAACATGGAGTCTTGATTGAAAATGGACTTTTTCAAACTATTTTATTTAATTAATTAAtttatttatttttgagatggagtctcgctctgttgcccaggc
Downstream sequence
tagagtgcagtggcacaatcttggctcattgcgacctctgtctcctgggttcaagtgattctcctgtcacagcctcctgagtagctaggattacaggcat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate