Basic Information
VIS ID
TVIS44018685
Fusion event
HTLV-1-MTCO1P12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
567556/632176 (Hg38)
End
567556/632176 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
MTCO1P12
Nearest miRNA
hsa-mir-1302-2/Upstream/444218; hsa-mir-101-1/Downstream/439;
Nearest TSS
ENST00000473358/Upstream/44508; ENST00000422528/Downstream/54497;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/20907, chr1-CpG: 60/Downstream/146428
Upstream sequence
TCTGCTGCAGTGCTCTGAGCCCTAGGATTTATTTTTCTTTTCACCGTAGGTGGCCTGACTGGCATTGTATTAGCAAACTCATCACTAGACATCGTACTAC
Downstream sequence
ACGACACGTACTACGTTGTAGCCCACTTCCACTATGTCCTATCAATAGGAGCTGTATTTGCCATCATAGGAGGCTTCATTCACTGATTTCCCCTATTCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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