Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene6700539766533383667482996675245966778787667271686673119466732118667342426675742666759241667514406675308066764439667654506672600066726400667432636674350466769390
Basic Information
VIS ID
TVIS44018691
Fusion event
HTLV-1-TCTEX1D1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
67235073/66769390 (Hg38)
End
67235073/66769390 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
TCTEX1D1
Nearest miRNA
hsa-mir-101-1/Upstream/140873; hsa-mir-11399/Downstream/1414128;
Nearest TSS
ENST00000473358/Upstream/16858; ENST00000448074/Downstream/5656;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16780, chr1-CpG: 27/Downstream/155807
Upstream sequence
ACCCTAATTTATCATGTAAGTTGTATTGCATTAAAGGATTTTTAAAAATAGATTACCCGTGATTTTCTTAAAATATCGATTTGCAAGAAGTTCATTAATT
Downstream sequence
CCAAACAGCGTAGAACTAAGTATTTTAAATTCCTTGCAAGAAAAAAGATCCCCAAAGATTAAGAGCAAATATCTATTTTTTATTTAATTAAAGCAAAAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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