Basic Information
VIS ID
TVIS44018694
Fusion event
HTLV-1-LINC01707 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.2
Reference genome
GRCh37/hg19
Start
69539102/69073419 (Hg38)
End
69539102/69073419 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1C ; FRA1L
Target gene
LINC01707
Nearest miRNA
hsa-mir-101-1/Upstream/889809; hsa-mir-11399/Downstream/1994212;
Nearest TSS
ENST00000473358/Upstream/17521; ENST00000448001/Downstream/176004;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/576096, chr1-CpG: 131/Downstream/493865
Nearby gene
DEPDC1-AS1(No orient, 534792)
Upstream sequence
gtctggaggatagtggccctcttttcatgcctccactaggtggtgccccagtagggactctgtgtggtagcttcaaccccaaatttcccttccacactgc
Downstream sequence
cctagtagaggttctccatgagagccccgctgctgcagcaaacttctgcctgggcatccaggagtctctgtaagtcttctgaaatctaggcggaggttcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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