Basic Information
VIS ID
TVIS44018695
Fusion event
HTLV-1-LINC01707 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.2
Reference genome
GRCh37/hg19
Start
69552815/69087132 (Hg38)
End
69552815/69087132 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1C ; FRA1L
Target gene
LINC01707
Nearest miRNA
hsa-mir-101-1/Upstream/903522; hsa-mir-11399/Downstream/1980499;
Nearest TSS
ENST00000473358/Upstream/31234; ENST00000448001/Downstream/162291;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/589809, chr1-CpG: 131/Downstream/480152
Nearby gene
DEPDC1-AS1(No orient, 548505)
Upstream sequence
TGGGGTGAAATTTCAGAGGAAGGGTAAAGCATGTGATCTCACACGCTATGTTCTAGCCACAATAATAGCTCATAGGTATAAGATAATTTTCCAGAGGTCC
Downstream sequence
TATGAgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtAACTTTTTCCCATCAACCCAACAATGCTAAGCTCTAAGctctaggtttaaaatatctggtt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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