Basic Information
VIS ID
TVIS44018716
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
87239950/86774267 (Hg38)
End
87239950/86774267 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/416580; hsa-mir-11399/Downstream/7072565;
Nearest TSS
ENST00000473358/Upstream/40023; ENST00000591456/Downstream/59902;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68935, chr1-CpG: 89/Downstream/140212
Nearby gene
SH3GLB1(+26083) ;
Nearest cancer related gene
SH3GLB1(TSG, +26083) ;
Upstream sequence
CCGCTATGATTAATGACTAAAGAATAAGAGCAGGTGTACAATCTTTATACATTTTAGATTTGGATCAAATTCACTCTTCTCAATTCCTCTTCCTAAAGCC
Downstream sequence
CCACCAATAATCCTTTGCCATCTGCCCCTCCTCCCCTTTCCTTTCTGAGGCTGCTAATGAAAGTGGGGTGGCCAGGACTGAAGAAGGACTTGAGCTGGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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