Basic Information
VIS ID
TVIS44018719
Fusion event
HTLV-1-LOC105378849 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
90693858/90228300 (Hg38)
End
90693858/90228300 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
LOC105378849
Nearest miRNA
hsa-mir-101-1/Upstream/3870613; hsa-mir-11399/Downstream/3618532;
Nearest TSS
ENST00000473358/Upstream/233163; ENST00000425185/Downstream/305172;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/232622, chr1-CpG: 67/Downstream/478245
Nearby gene
ZNF326(+199764) ;
Upstream sequence
tcagcaggtttggtttcttctgaggcctctttacttggcttgcagatggctgccttcttgatgtgtcctcacaaggttgcccctgaatctgtgtgttgcc
Downstream sequence
tgtgtactaatttcctctccttataaggacactagtcctatcagactatggcctgcctatatgacctcattttatcttatttacctctttaaaggtgtta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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