Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene1183947911482341116427881165817811670164116117301161263911610543116112291161831511618787116483081164863011635913116361701161756811617798116280041162819811660910
Basic Information
VIS ID
TVIS44018754
Fusion event
HTLV-1-NTSR2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
11801036/11660910 (Hg38)
End
11801036/11660910 (Hg38)
Orient
-
Location type
Intronic
Target gene
NTSR2
Nearest miRNA
hsa-mir-4261/Upstream/120233; hsa-mir-10b/Downstream/106534;
Nearest TSS
ENST00000437798/Upstream/48567; ENST00000464517/Downstream/9254;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/3800, chr2-CpG: 92/Downstream/8613
Upstream sequence
TGGTTAATTTACAGCACTGCCATTCATCTGGCACTCAAGCCATAAGCCAGAGACTCCTATTTTTCTGTTCCTTTCTATATCCAGTCTATTGAAAAGTTCC
Downstream sequence
TTCTTAGCATCTCTCCTCTGTGCTTTCCCTGCTCTCACTGCTACCTCCCTAAGAGACTCTTACCGCCTCTGTACTGGACTATGACGAGTTTCCCAACCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate