VISDB Viral Integration Site DataBase

VIS ID

TVIS44018768

Fusion event

HTLV-1-CYP27C1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q14.3

Reference genome

Start

End

127960469/127202893 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1273h-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-3158-5p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-7705 ; hsa-mir-6854-5p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-129-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-6881-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-874-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-4749-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6078 ; hsa-mir-877-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-6887-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-1299 ; hsa-mir-7107-3p ; hsa-mir-6753-3p ; hsa-mir-6503-5p ; hsa-mir-4527 ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-4732-3p ; hsa-mir-4716-5p ; hsa-mir-4781-3p

Nearest miRNA

hsa-mir-1285-2/Upstream/13481525; hsa-mir-10b/Downstream/220644;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/95181, chr2-CpG: 148/Downstream/15920

Upstream sequence

gtttaaaagacctgaatttgaaactaactttctgcctctaaaaagagggatgggggtgtggcattgggcaagttcttttttaagtccagtttcagccagg

Downstream sequence

tgcagtggctcatgcctgtaatcccagcactttgggaggccaaggcgggcgaatcacgaggtcaggagttcgagaccagccttgccaacatggtgaaaca