Basic Information
VIS ID
TVIS44018777
Fusion event
HTLV-1-MIR7853 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
133877955/133120382 (Hg38)
End
133877955/133120382 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
MIR7853
Nearest miRNA
hsa-mir-1285-2/Upstream/686562; hsa-mir-10b/Downstream/1006743;
Nearest TSS
ENST00000437798/Upstream/204825; ENST00000454699/Downstream/144586;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/449085, chr2-CpG: 52/Downstream/145993
Upstream sequence
AGGCTGTTTGTTAGCAACAGATGTAGACATTTATAAACAAGGACCATCTTAACAGAATTATTTCTCACGAATTAAATAAAGGATCCCAAAGAATGGTTCC
Downstream sequence
AACTGTTTACAGTTAGCACTTAGACTTATACTATGTGGGAACAGTGTTCATTAAATGCACTGCCTATGGACCATAAAGGTAATCAGAACAACAATCTATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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