Basic Information
VIS ID
TVIS44018778
Fusion event
HTLV-1-LOC105373436 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
13464819/13324694 (Hg38)
End
13464819/13324694 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373436
Nearest miRNA
hsa-mir-3125/Upstream/587250; hsa-mir-10b/Downstream/6023735;
Nearest TSS
ENST00000437798/Upstream/606456; ENST00000434509/Downstream/212979;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/605801, chr2-CpG: 248/Downstream/1307559
Nearby gene
LOC100506474(-317681) ;
Upstream sequence
AATTAATATCTGATTAATTAGTAATCAAATACCAAATGAATATTTTTATTCATAGATATTGTATGGAAAAGTCTGCACCTCATTCCAAAATCATGTTGAA
Downstream sequence
GTGGAAACTTTTTCAACAAACATATTTCATAGTGTAGCATGGCATAGCTTCTGACATCTGTACTCTTAGCCCATTTAGAAAGTATGAAAACTCAAGATCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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