Basic Information
VIS ID
TVIS44018784
Fusion event
HTLV-1-LOC105373643 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
140108781/139351211 (Hg38)
End
140108781/139351211 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373643
Nearest miRNA
hsa-mir-128-1/Upstream/3685733; hsa-mir-10b/Downstream/1235415;
Nearest TSS
ENST00000437798/Upstream/570863; ENST00000429008/Downstream/14954;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/570131, chr2-CpG: 58/Downstream/2778944
Nearby gene
YY1P2(No orient, 452037)
Upstream sequence
TAGAAATGGGAAATGTAGATCTAGAAGTACACTAAGAAGACGCTTAGCCTGACACATGTGTTTTATTAAAGGATTTCAGCTACTTTGGTAGATAGCTTTC
Downstream sequence
TTTTTCTGTTTCACGTATTCATTAAAACAATTGTAAAATATTCAATGGCAAACAGAATCCTAGTATTTTGTATTTTTGTATGTAGCACAGAGGCTGTACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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