Basic Information
VIS ID
TVIS44018800
Fusion event
HTLV-1-DPP4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
162871614/162015104 (Hg38)
End
162871614/162015104 (Hg38)
Orient
-
Location type
Intronic
Target gene
DPP4
Nearest miRNA
hsa-mir-128-1/Upstream/1607222; hsa-mir-10b/Downstream/6567839;
Nearest TSS
ENST00000437798/Upstream/642; ENST00000418335/Downstream/2447;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/507215, chr2-CpG: 63/Downstream/58619
Nearest cancer related gene
DPP4(TSG, No orient, 0)
Upstream sequence
GAGCAAACTGTTGCGTACATTCTGTATGATCTCCCACGGGTCTGTCTCATTCTCTGTGCTTGATTTAACATCAGTTTAATAAAATTTGTCCCTAAATAAT
Downstream sequence
GAGTCAGTTTCCTTCGTTCCCAAATAAAAGATGAGTTATACTAATAGATCTATAAAAAAGTGTTTTTCCACATTTAAATAAAATTATTCCAGATTCAGTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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