VISDB Viral Integration Site DataBase

VIS ID

TVIS44018802

Fusion event

HTLV-1-CSRNP3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q24.3

Reference genome

Start

End

166366739/165510229 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-5p ; hsa-mir-126-5p ; hsa-mir-4795-3p ; hsa-mir-6849-3p ; hsa-mir-7977 ; hsa-mir-548p ; hsa-mir-4729 ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-3689a-5p ; hsa-mir-3689b-5p ; hsa-mir-3689e ; hsa-mir-3689f ; hsa-mir-5011-5p ; hsa-mir-510-3p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-3924 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5186 ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-297 ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5580-3p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-6840-3p ; hsa-mir-1272 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-3668 ; hsa-mir-6507-5p ; hsa-mir-4303 ; hsa-mir-6761-5p ; hsa-mir-4251 ; hsa-mir-4329 ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-7844-5p ; hsa-mir-4778-5p ; hsa-mir-374a-3p ; hsa-mir-513b-5p ; hsa-mir-7848-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-504-5p ; hsa-mir-548e-5p ; hsa-mir-4646-3p ; hsa-mir-2355-3p ; hsa-mir-5696 ; hsa-mir-3912-5p ; hsa-mir-15b-3p ; hsa-mir-1295b-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-587 ; hsa-mir-607 ; hsa-mir-6715b-3p ; hsa-mir-4650-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-5680 ; hsa-mir-548m ; hsa-mir-4789-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-942-5p ; hsa-mir-130b-5p ; hsa-mir-5692a

Nearest miRNA

hsa-mir-128-1/Upstream/5102347; hsa-mir-10b/Downstream/3072714;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/667846, chr2-CpG: 94/Downstream/283170

Upstream sequence

agtgtctgcaagatttatccactgtagcattactatttttattttttcacgctctgtttttttgaaataactaacccaacccaggtcacactcaaggtcg

Downstream sequence

atggtggtgatcaagctttgcttcttaaatggggatgatctgtatatgttctttggaaactttttgtaaggaacagtttttctcttctctctcatttact