VISDB Viral Integration Site DataBase

VIS ID

TVIS44018810

Fusion event

HTLV-1-LNPK integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q31.1

Reference genome

Start

End

176822917/175958189 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-let-7b-3p ; hsa-mir-93-5p ; hsa-mir-1260b ; hsa-mir-340-5p ; hsa-mir-6847-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-4528 ; hsa-mir-3163 ; hsa-mir-1276 ; hsa-mir-7150 ; hsa-mir-644a ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6799-5p ; hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6134 ; hsa-mir-20b-3p ; hsa-mir-5693 ; hsa-mir-6798-5p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4795-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-3140-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-100-3p ; hsa-mir-4701-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4707-3p ; hsa-mir-6506-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-150-5p ; hsa-mir-6765-3p ; hsa-mir-1228-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-619-5p ; hsa-mir-6773-3p ; hsa-mir-548g-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-148a-5p ; hsa-mir-202-5p ; hsa-mir-22-5p ; hsa-mir-337-3p ; hsa-mir-4694-3p ; hsa-mir-4698 ; hsa-mir-5584-3p ; hsa-mir-6875-3p ; hsa-mir-8063

Nearest miRNA

hsa-mir-128-1/Upstream/790480; hsa-mir-10b/Downstream/192114;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/776413, chr2-CpG: 48/Downstream/43776

Upstream sequence

accaggcctgcctgcctctgtagactccacctctgggggcagggcatagctgaacaaaaggcagcagaaacttctgcagacttaaaatgtccctgtctga

Downstream sequence

cagctctgaagagagcactggttctcccagcatggagtttgagctctgagaacagacagactgcctcctcaagtgggtccctgaccactgtgtagcctaa