Basic Information
VIS ID
TVIS44018819
Fusion event
HTLV-1-LOC105373456 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
18896458/18715192 (Hg38)
End
18896458/18715192 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2C
Target gene
LOC105373456
Nearest miRNA
hsa-mir-3125/Upstream/5977748; hsa-mir-10b/Downstream/633237;
Nearest TSS
ENST00000437798/Upstream/125620; ENST00000431697/Downstream/69615;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/130278, chr2-CpG: 71/Downstream/632529
Nearby gene
NT5C1B-RDH14(-125612) ;
Upstream sequence
GTCAGCCCCTCCAGGCTCTGTTGCTGCTGGGAATACTGGCCTGCTGTCACTGACAGGTGTGGGCAAGGGATAGGTTGGCTACCCAAGATCTTGTGGCGTG
Downstream sequence
GCTGCTGCAGGTAGATTAGGCATCATTGCCACAATCCCAAGTCCCCACTGGGCTTTTCTTCCCTGATCTTTTGGTCAGAGAGAGAAGAGTCCTTTTCTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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