Basic Information
VIS ID
TVIS44018834
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
213570785/212706061 (Hg38)
End
213570785/212706061 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/279701; hsa-mir-1244-1/Downstream/220196;
Nearest TSS
ENST00000437798/Upstream/167220; ENST00000434559/Downstream/89270;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/167538, chr2-CpG: 180/Downstream/125564
Upstream sequence
CCTCCAAAGCCCTTCCCACTGACTTGTACTTATGATTCCTTGGTCGTACCTATGAGAAAGGGAAAGCTAGGCAGTACACTCTTCTAAATGGGTTGCTCCC
Downstream sequence
GCCAtgaataaaaccaggttatgttagtaaggcaaaaggggagaatagctattggctgggtcactagaagtcattgccaAAGTCACAGAAGTTCTTCCTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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