VISDB Viral Integration Site DataBase

VIS ID

TVIS44018839

Fusion event

HTLV-1-TNS1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

218730448/217865725 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-4446-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-4279 ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-627-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3679-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-22-5p ; hsa-mir-6887-3p ; hsa-mir-3691-3p ; hsa-mir-5584-3p ; hsa-mir-148a-5p ; hsa-mir-942-5p ; hsa-mir-6783-5p ; hsa-mir-8055 ; hsa-mir-6739-3p ; hsa-mir-375 ; hsa-mir-1304-5p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-6868-3p ; hsa-mir-8068 ; hsa-mir-4326 ; hsa-mir-5087 ; hsa-mir-4751 ; hsa-mir-5004-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-548j-5p ; hsa-mir-142-5p ; hsa-mir-33a-5p ; hsa-mir-33b-5p ; hsa-mir-340-5p ; hsa-mir-4666a-3p ; hsa-mir-4729 ; hsa-mir-5590-3p ; hsa-mir-5700 ; hsa-mir-586

Nearest miRNA

hsa-mir-10b/Upstream/4107566; hsa-mir-1244-1/Downstream/34788;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/108950, chr2-CpG: 30/Downstream/112933

Upstream sequence

AAAGATGTAAAGATTGGGCAGTCTGAAGCTCCCCACATCCATCAACAGCTCTGTTGCTGCTTCCCAGGGCACAGGGAGATAAATGGCCCAGGGATTGAAC

Downstream sequence

AACTGAGGTCCAGTATTCTGGAGCCAGGAGTGTCTGAGGCAGGACACCCCAGGTCCCTGAGGGATAGTCTTGTGAGTGTAAATAATGCTTGAGCAAAGAA