Basic Information
VIS ID
TVIS44018841
Fusion event
HTLV-1-LOC105373893 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
221309143/220444422 (Hg38)
End
221309143/220444422 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373893
Nearest miRNA
hsa-mir-10b/Upstream/537857; hsa-mir-1244-1/Downstream/4566039;
Nearest TSS
ENST00000437798/Upstream/316876; ENST00000414512/Downstream/6257;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/816357, chr2-CpG: 260/Downstream/1126588
Nearby gene
MIR4268(-537857) ;
Upstream sequence
gtttggcactagcatgccagtagcacccctaagttgagaccaccagaaaaagtctccagacactgccaaaattctctgTTTGAGACCTATTGTGGTATGA
Downstream sequence
TATAATGCTGGAATCAGAAaaatcttttctttaaagggccagatagtaaatattttcaggcttgtgacatggtctttgttgttgggcagccactcaaatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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