Basic Information
VIS ID
TVIS44018845
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
231189934/230325219 (Hg38)
End
231189934/230325219 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/2853032; hsa-mir-1244-1/Downstream/1037489;
Nearest TSS
ENST00000437798/Upstream/15078; ENST00000458341/Downstream/1965;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/256385, chr2-CpG: 125/Downstream/387375
Nearby gene
SP140L(+1960) ;
Upstream sequence
TACTTCTTAATTTGGTCCTGTCCCTTTCCCAACCCAGGTGTGTCTGATGTATTCCAGATCAAAGAAACTTTGCTTTTCCCACAGAAGCCTAGAGATTCTC
Downstream sequence
CATTAACTGGCATTGCTTTTGCAGAGTGTGGTGTGTGCTCAGCTTTTTCCAACCCTGTCTGACAAGAACATCTCCTTCCCTGCTGTCAGGAGCTGCCCTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate