Basic Information
VIS ID
TVIS44018847
Fusion event
HTLV-1-NGEF integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
233747611/232882901 (Hg38)
End
233747611/232882901 (Hg38)
Orient
-
Location type
Intronic
Target gene
NGEF
Nearest miRNA
hsa-mir-10b/Upstream/332328; hsa-mir-149/Downstream/4628030;
Nearest TSS
ENST00000437798/Upstream/6380; ENST00000233840/Downstream/2635;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/5732, chr2-CpG: 20/Downstream/18238
Upstream sequence
tccacagttccaggctcaagGCCTGCAAAGCATCTCTCCCCACATTTAGCTTGCTTGTCCCTCGTGGGGGGCCTAGGGCTGCAGGGCAGGGGTCCCAGCT
Downstream sequence
gctcagagaggtgaagagatgagctcaatgccacacagcaagtggcagCAGGGAGCAGGAGGATGGTGGTTCCCTACTCAGCCTGACTCAAGGGTTCTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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