VISDB Viral Integration Site DataBase

VIS ID

TVIS44018849

Fusion event

HTLV-1-TRAF3IP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q37.3

Reference genome

Start

End

239275876/238367235 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-1298-5p ; hsa-mir-4672 ; hsa-mir-205-5p ; hsa-mir-3927-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-3613-3p ; hsa-mir-6768-5p ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548n ; hsa-mir-6776-5p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-143-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4743-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-490-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-517c-3p ; hsa-mir-7856-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-4781-3p ; hsa-mir-501-5p ; hsa-mir-22-3p ; hsa-mir-1264 ; hsa-mir-3184-3p ; hsa-mir-320e ; hsa-mir-1273a ; hsa-mir-1273g-3p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4432 ; hsa-mir-4486 ; hsa-mir-4649-5p ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-499a-5p ; hsa-mir-508-5p ; hsa-mir-616-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-8087 ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-10b/Upstream/856247; hsa-mir-149/Downstream/701582;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/46440, chr2-CpG: 122/Downstream/59284

Upstream sequence

cctgggtgacaaagcaagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaaagaaaaTTAGTGGATAAGGATTAGAATTAAATAGAATTTAGTCACAT

Downstream sequence

TGACTACTAAACAATGCCCCAGCTCAGTGGAGAGAAGTGTAGGAGGTATCTGGAGAGCAGTAAGTAGAGAAATCAAAGGGGATGTGGCACAAGTTTCAGA