Basic Information
VIS ID
TVIS44018852
Fusion event
HTLV-1-LOC105373966 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
240581643/239659949 (Hg38)
End
240581643/239659949 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
LOC105373966
Nearest miRNA
hsa-mir-10b/Upstream/308145; hsa-mir-149/Downstream/283066;
Nearest TSS
ENST00000437798/Upstream/34251; ENST00000567853/Downstream/75007;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/14999, chr2-CpG: 26/Downstream/30686
Nearby gene
LOC150935(+102911) ;
Upstream sequence
ttggtcaggctggtctggaactcctgacatcagatgatcagcccgcctcggcctcccatagtgctgggattacaggtgtgagccaccgcgcctggccTGG
Downstream sequence
CCTCACGTTTTCTGTTTGATTTCTCTCAATAGAATCCTTGTGTGGGGCCTCGAAGCTGACTGACCACACCCCTGCCTCCGCCCTAAACTTGCGTCTGGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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