VISDB Viral Integration Site DataBase

VIS ID

TVIS44018861

Fusion event

HTLV-1-SPAST integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p22.3

Reference genome

Start

End

32290749/32065680 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-32-3p ; hsa-mir-1250-3p ; hsa-mir-335-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-190a-3p ; hsa-mir-5687 ; hsa-mir-627-3p ; hsa-mir-5011-5p ; hsa-mir-6758-3p ; hsa-mir-153-5p ; hsa-mir-1285-5p ; hsa-mir-665 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-1273e ; hsa-mir-6514-3p ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-3192-5p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7851-3p ; hsa-mir-302f ; hsa-mir-490-3p

Nearest miRNA

hsa-mir-1301/Upstream/4069231; hsa-mir-10b/Downstream/466473;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/1283, chr2-CpG: 22/Downstream/99928

Upstream sequence

GAAGTCTAACTTTTACAATTCTCCCCTTTTATCCTTACTTCCAGTATGCTGAGATCTTGCTTCTCCCTCTGCCAAAAACACCCACTTTTCTACCACACCT

Downstream sequence

CAATTAGATACTCACTTGCATTGTCCATTAGTGAAAACAGAAACAATCTGCACTTCATTCATAGTGTCTGTCTCTACTGCCAACTCCAAAAACTGTTCTA