Basic Information
VIS ID
TVIS44018862
Fusion event
HTLV-1-LINC01320 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
34910464/34685397 (Hg38)
End
34910464/34685397 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01320
Nearest miRNA
hsa-mir-1301/Upstream/1266833; hsa-mir-10b/Downstream/786008;
Nearest TSS
ENST00000437798/Upstream/7498; ENST00000607437/Downstream/8901;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/957780, chr2-CpG: 191/Downstream/1669857
Upstream sequence
TAACTGGCTCAGTTACATGAACAATTTACGAATTGATCTCATTTATCAGATATTTATAACCAATAGTCAATCAAATAAAGACTTTTTTATTTTACTTTCC
Downstream sequence
CTCTATCTGATAAGTAAAATAATATTCTAGCATGGTGCTACATTTCAAATAGTACAAAACAAATTAAACTCTTAATGGTCTATAACATATAGACCTAGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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