Basic Information
VIS ID
TVIS44018867
Fusion event
HTLV-1-ALLC integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
3729402/3681812 (Hg38)
End
3729402/3681812 (Hg38)
Orient
+
Location type
Intronic
Target gene
ALLC
Nearest miRNA
hsa-mir-10b/Downstream/2292850;
Nearest TSS
ENST00000437798/Upstream/23617; ENST00000471711/Downstream/12809;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/29937, chr2-CpG: 125/Downstream/21426
Upstream sequence
GGTACATCTCCCCCAAATGAATTGGGTCTTGTCACCAATTATTAGGAGAGTAGGGAAACTGCTCTGCACACCTGGCTGTGCAAGGCGATTCTTTGGGACG
Downstream sequence
CCCAGCCCTGATGCTCCCCACATCATTTGCTTACCCACTGTGGCCTTGCAAACGTCTCAGTGGTTCATCAACCTGGGAAGAGTGAGCATCATGGCCCAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate