Basic Information
VIS ID
TVIS44018868
Fusion event
HTLV-1-LOC105374464 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
37834824/37607681 (Hg38)
End
37834824/37607681 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374464
Nearest miRNA
hsa-mir-1301/Upstream/2136195; hsa-mir-10b/Downstream/9769994;
Nearest TSS
ENST00000437798/Upstream/7545; ENST00000431712/Downstream/39977;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/262427, chr2-CpG: 167/Downstream/63318
Nearby gene
CDC42EP3(-34201) ;
Upstream sequence
gaggagaaagaggtggaagaggcaggcacacttggtgttacttttattgaaaaaaaatcctcatttaagtagacctatgcagtccaaatttgtgttgttc
Downstream sequence
aaggggcaattTTAACTATATAGCTATAATAGGTTAACAgatacacaatataaaaagatggaaattttgacatcactaacataaaataggtggggtggag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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